Use NSAIDs Cautiously
NSAIDs for chronic pain should be taken under the supervision of a doctor to minimize risks.

Use NSAIDs Cautiously

Nonsteroidal anti-inflammatory drugs (NSAIDs) can be effective pain relievers, but know the potential risks.

COX-2 inhibitors were developed to avoid the stomach problems that can occur with traditional NSAIDs. The COX-1 enzyme protects the stomach lining from corrosive effects of stomach acid, so it was thought that inhibiting just COX-2 would be easier on the stomach. But COX-2 also has a protective effect. The risk for stomach issues is about 50% lower with COX-2 inhibitors than with nonselectiveNSAIDs.

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    Pain Management

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    Pain Management

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    Pain Management

    Download The Full October 2019 Issue PDF

    NSAIDs are effective because they block an enzyme called cyclooxygenase (COX), which exists in two forms—COX-1 and COX-2. These enzymes make chemicals called prostaglandins, which contribute to inflammation in the body.

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