Research Roundup: November 2025

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Methotrexate Does Not Improve Knee Osteoarthritis Symptoms in New Trial Methotrexate is a medication used for rheumatoid arthritis that has recently shown some promise in treating knee osteoarthritis. A randomized study published in the June 2025 JAMA Internal Medicine did not find low-dose methotrexate (up to 15 milligrams weekly) effective at improving pain or effusion-synovitis. Effusion […]
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