Cancer immunotherapy treatment using immune checkpoint inhibitors (ICIs) have revolutionized treatment for many cancers in the last 15 years. “ICIs work by activating the body’s immune system to fight cancer and can sometimes lead to the immune system attacking healthy tissues,” says rheumatologist Cassandra Calabrese, DO, who holds a dual appointment in Rheumatology and Cancer at Cleveland Clinic. Dr. Calabrese specializes in the diagnosis and management of immune-related adverse events (irAEs) that arise from cancer immunotherapy. See “What You Should Know,” on page 7.
Can Cancer Treatment Cause Arthritis?
Medications that help the body attack cancer sometimes incite inflammatory arthritis
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