For many patients, medications seem like a one-size-fits-all solution. After all, most over-the-counter drugs carry just one dose recommendation for all adults. But getting the right amount of medicine is more complicated than that. In fact, researchers are increasingly unlocking the multiple factors, including your own genetic makeup, that affect how much medicine you should take. Bottom line: You need to be vigilant about asking whether the dose youre taking is right for you." There is always a danger in getting the wrong dose of a medication, and some drugs are more of a concern than others," says Mandy C. Leonard, Pharm.D., BCPS, assistant director for Drug Information Services and Formulary Management at Cleveland Clinic. Depending on the medication, several factors can affect whether youre getting the proper dose, Leonard says.