People with painful knee osteoarthritis often take nonsteroidal anti-inflammatory drugs (NSAIDs). If these drugs fail to provide adequate relief, opioid drugs may be the next step. The bone-thinning disease osteoporosis may be more common in women, but men can get it too. Keeping bones strong is important for staving off this condition, and the earlier the better. Being overweight or obese is a well-known risk factor for osteoarthritis, especially in the knees. Low back pain is extremely common and can occur for many reasons. Regardless of the underlying cause, exercise to improve strength and support often is recommended.