Features December, 2006 Issue

Gene Study May Spark New OATreatments

Research is underway at Cleveland Clinic to determine whether two genes required to form the cartilage structures that progressively change into bone as we grow older may lead to new ways of replenishing destroyed cartilage.

According to a recent report in Cleveland Clinic Magazine, molecular biologist Veronique Lefebvre, Ph.D., and her research team have discovered two genes Sox5 and Sox6 required to form cartilage that progressively changes into bone as we age. On reaching adulthood, we…

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