Ask The Doctors: July 2025

SAMe supplements..... Calcium absorption from foods

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Q. Is there sound research on the SAMe supplement for arthritis pain?

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S-Adenosylmethionine (SAMe) is a naturally occurring compound in the body. A synthesized version is available as a supplement in the United States. SAMe is thought to stimulate cartilage growth and have anti-inflammatory, antidepressant and pain killing effects. It may help reduce functional limitations from ­osteoarthritis.

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