The cost of medications seems to go in only one direction these days-up. To help you keep a lid on rising drug costs, here are several strategies-beyond pill-splitting and generics, two tactics you probably have already tried-that might help. Some of these steps you can take on your own, but all of them should be discussed with your doctor before you begin. Many of the new medications to treat arthritis can be frighteningly expensive. And even in the best of circumstances, the drugs may only be helpful to 50 percent of those who take them. "With each medication, you need to know why youre taking it and how long to wait before expecting results," says Cari Cristiani, a Cleveland Clinic pharmacist. "If its not working, ask your doctor if its time to stop taking it and switch to something else."