For most people who develop carpal tunnel syndrome (CTS), proper treatment usually can relieve pain, numbness, tingling, and restore normal function of the wrist without surgery. In the early stages of CTS, a night splint is the first treatment recommended. This splint keeps the wrist in a neutral position during sleep, minimizing pressure on the median nerve and relieving the nighttime symptoms of tingling and numbness. The splint can also be effectively used during the day. Splinting is most effective in patients who have moderate symptoms of short duration.