Osteoarthritis: More Than Damaged Cartilage

Research suggests a role of fat cells, inflammation, and bone dysfunction as potential targets for OA treatment.

Conventional wisdom has held that osteoarthritis (OA) is solely a wearing out of your joint cartilage, while rheumatoid arthritis (RA) is caused by inflammation, an errant immune response. However, OA and RA may have more in common than once believed. New evidence points to an inflammatory component of OA, and it suggests that obesity not only places undue stress on your knees and hips, but also may damage all of your joints more insidiously, at a cellular level. In addition, researchers are recognizing the vital role of the bone underneath the cartilage, prompting a closer look at the whole joint as it relates to OA. Experts hope this new understanding will translate into new strategies to prevent and treat OA, the most common form of arthritis and a disease with limited medical treatments.
To continue reading this article or issue you must be a paid subscriber. Sign in

Subscribe to Arthritis Advisor

Get the next year of Arthritis Advisor for just $20. And access all of our online content - over 1,000 articles - free of charge.
Subscribe today and save 36%. It's like getting 4 months FREE!
Already Subscribed?
Click Here to Sign In | Forgot your password? | Activate Web Access